Lone Ranger departed from Las Palmas, Canary Islands on January 11, 2011, to cross the Atlantic for its maiden scientific cruise entitled "2011 Lone Ranger Marine Pollutants Atlantic Expedition".

An onboard coalition of scientists led by Dr. Erika (Raymond) Montague, SOI Fellow, MBARI Postdoctoral Researcher, and the Chief Scientist for this expedition, endeavored to explore approximately 3,000 nautical miles of the North Atlantic Gyre through the Sargasso Sea to study ocean pollutants. Researchers targeted microbes that could serve as new energy sources, and investigated the composition, structure, and biochemical dynamics of pollutants across the North Atlantic.  The expedition concluded in Bermuda on January 29, 2011.